關(guān)文月 副研究員 

      E-mail：[email protected]

  辦公地點：南京市四牌樓2號，李文正樓北208室

教育和工作簡歷：

2006.09-2010.07河南師范大學(xué)，生物科學(xué)，學(xué)士

2010.09-2012.07華東師范大學(xué)，生化與分子生物學(xué)，碩士

2012.09-2017.10法國里昂高等師范，生化與分子生物學(xué)，博士

2017.10-2022.04法國里昂基因功能研究所，博士后

2022.09-2024.01昌平國家實驗室，副研究員

2024.02-至今東南大學(xué)，生命科學(xué)與技術(shù)學(xué)院，副研究員

研究方向：

1. 性別特異性神經(jīng)環(huán)路的建立與調(diào)控機制

2. 個體行為抉擇/輸出的神經(jīng)與環(huán)路調(diào)控機制

代表性論文：

1. Wenyue Guan; Ziyan Nie; Anne Lauren?on; Mathilde Bouchet; Christophe Godin; Chérif Kabir; Aurelien Darnas; Jonathan Enriquez; The role of Imp and Syp RBPs in precise neuronal elimination by apoptosis through the regulation of TFs, eLife, 2023.

2. Mathilde Bouchet; Séverine Urdy; Wenyue Guan; Chérif Kabir; Steve Garvis; Jonathan Enriquez ; A simple smiFISH pipeline to quantify mRNAat the single-cell level in 3D, STAR protocols, 2023, 4(2).

3. Wenyue Guan; Stéphanie Bellemin; Mathilde Bouchet; Lalanti Venkatasubramanian; Camille Guillermin; Anne Lauren?on; Kabir Chérif; Aurélien Darnas; Christophe Godin; Séverine Urdy; Richard Mann; Jonathan Enriquez; Post-Transcriptional Regulation of Transcription Factor Codes in Immature Neurons Drives Neuronal Diversity, Cell Reports, 2022, 39(13).

4. Wenyue Guan; Romain Guyot; Frédéric Flamant; Two protocols to study the interactions of thyroid hormone receptors with other proteins and chromatin, Methods in Molecular Biology, 2018.6, 1801: 9-16.

5. Wenyue Guan; Lalanti Venkatasubramanian; Myungin Baek; Richard S Mann; Jonathan Enriquez; Visualize Drosophila Leg Motor Neuron Axons Through the Adult Cuticle, Journal of Visualized Experiments, 2018, (140).

6. Suzy Markossian; Romain Guyot; Sabine Richard; Marie Teixeira; Nadine Aguilera; Mathilde Bouchet; Michelina Plateroti; Wenyue Guan; Karine Gauthier; Denise Aubert; Frédéric Flamant; CRISPR/Cas9 Editing of the Mouse Thra Gene Produces Models with Variable Resistance to Thyroid Hormone, Thyroid, 2018.11, 28(1): 139-150.

7. Wenyue Guan; Romain Guyot; Jacques Samarut; Frédéric Flamant; Jiemin Wong; Karine Gauthier; Methylcytosine dioxygenase TET3 interacts with thyroid hormone nuclear receptors and stabilizes their association to chromatin, Proceedings of the National Academy of Sciences of the United States of America, 2017, 114(31): 8229-8234.

8. Rulai Han; Lei Ye; Xiaohua Jiang; Xiaoyi Zhou; Cyrielle Billon; Wenyue Guan; Karine Gauthier; Weiyuan Fang; Weiqing Wang; Jacques Samarut; Guang Ning; Characteristics of patients with late manifestation of resistance thyroid hormone syndrome: a single-center experience, Endocrine, 2015.6, 50(3): 689-97.